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Scientists thought brain inflammation was driving long COVID but the scans told a different story

sciencedaily.com·May 28, 2026

A new study from the University of Turku revealed that long COVID symptoms are not primarily driven by widespread brain inflammation, as previously thought. Instead, the most severe symptoms correlate with increased activity in brain regions related to mood and emotion, suggesting that treatments focusing on stress management may be more beneficial for patients.

For professionals tracking neuroscience and scientific breakthroughs, the key insight from the University of Turku's study is the shift in understanding long COVID's neurological impact. Contrary to the belief that persistent brain inflammation causes prolonged symptoms, the study found increased brain activity in emotion-related regions, suggesting treatments should focus more on stress management and emotional regulation rather than solely targeting inflammation. This insight could influence future research directions and treatment strategies for long COVID.

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