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J&J Gets FDA Nod for Plaque Psoriasis Pill Positioned to Compete With Injectables - MedCity News

medcitynews.com·Mar 18, 2026

Johnson & Johnson has received FDA approval for Icotyde, an oral medication for moderate-to-severe plaque psoriasis, providing a new alternative to injectable therapies. The drug targets the IL-23 receptor, aiming to offer effective treatment with a favorable safety profile, and has the potential for significant market revenue as it expands to other conditions.

The FDA approval of Johnson & Johnson's new oral medication, Icotyde (icotrokinra), provides a significant advancement in the treatment of moderate-to-severe plaque psoriasis by offering a once-daily pill option that targets the IL-23 receptor, similar to existing injectable treatments. This development not only enhances treatment convenience for patients but also positions J&J to compete strongly in the psoriasis market, potentially generating over $5 billion in peak annual revenue. For investors and stakeholders in healthtech and biotech, this approval represents a critical milestone and a lucrative opportunity, especially given the drug's robust performance in clinical trials compared to existing oral options like Sotyktu.

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